Ashwagandha KSM-66: Premium Extract for Stress, Performance and Wellbeing - BPR Nutrition

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Ashwagandha KSM-66: The Most Studied and Powerful Form in the World

Ashwagandha KSM-66 is the patented extract of Withania somnifera (Indian Ginseng) with the higher concentration of active ingredients (5% withanolides) and the wider spectrum of clinical studies (over 22 published research). Produced through exclusive extraction from single root (most powerful part of the plant), KSM-66® guarantees efficacy, safety and purity higher than generic extracts.

Ashwagandha it's a plant tonic-adaptogenic thousand years of Ayurvedic medicine, used for:

• Reduce stress and anxiety (lowers cortisol by up to 27.9%)
• Improve physical and cognitive performance (strength, endurance, memory, concentration)
• Support natural testosterone (up to 17% increase in men)
• Strengthen immune system and resistance to stress
• Promote deep sleep and night recovery
• Reduce physical and mental tiredness

BPR Nutrition Ashwagandha 60 tablets offers you 500 mg of KSM-66® extract per tablet (titrated 5% withanolides = 25 mg per dose), the same formula used in clinical trials that demonstrated tangible benefits in 8-12 weeks. 60 tablets = 2 months of continuous integration.

If you search "ashwagandha ksm 66", you are looking for the guarantee of pharmaceutical quality, complete traceability and scientifically proven results. Not all ashwagandhas are the same: KSM-66® is the world's gold standard.

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Format and Duration

• Packaging: 60 tablets
• Portions: 60 doses (1 tablet per day)
• Dosage per tablet: 500 mg KSM-66® extract (25 mg withanolides)
• Duration: 2 months (60 days)
• Net weight: ~45-50g
• Packaging: Resealable jar in PET plastic

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Nutritional Values per Tablet

*VNR not applicable for plant extracts

Notes:

• 12:1 extraction: 500 mg extract = 6000 mg (6g) dry root equivalent
• Pharmaceutical form: Tablet (not capsule) for optimal release
• Zero unnecessary additives: Only essential excipients (cellulose, anti-caking agents)

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What Makes KSM-66® Superior?

1. Patented Extraction from the Root Only

• 100% Withania somnifera root (NO leaves, NO stems)
• Root contains maximum concentration withanolides (active ingredients)
• Leaves/stems: Different chemical profile, less effective, possible contaminants

Comparison:

• KSM-66®: Root only, full spectrum withanolides
• Generic extracts: Root+leaf mix, variable withanolides

2. Standardization 5% Withanolides (25 mg per tablet)

• Withanolides they are the active ingredients responsible for the adaptogenic effects
• Guaranteed titration 5%: Each tablet contains exactly 25 mg withanolides
• Non-standardized extracts: Withanolide content 0.5-3% (unpredictable)

Purity: KSM-66® is tested for absence withaferine (toxic components present in leaves)

3. Green Chemistry Production Process

• Extraction with only water and ethanol (NO aggressive chemical solvents)
• Controlled temperature: Preserves thermolabile substances (enzymes, phytocompounds)
• Sustainability: ISO 14001 certification (environmental management)

4. Over 22 Published Clinical Studies

• KSM-66® is the most studied ashwagandha in the world
• Studies on: stress, anxiety, cortisol, testosterone, muscle strength, endurance, cognition, sleep, fertility
• Peer-reviewed publications on: Journal of Alternative and Complementary Medicine, Journal of the International Society of Sports Nutrition, Evidence-Based Complementary and Alternative Medicine

5. Certifications and Quality

✅ GMP (Good Manufacturing Practices): Pharmaceutical production
✅ ISO 9001: Quality management
✅ HACCP: Food safety
✅ Organic Certified: Organic farming (raw material)
✅ Non-GMO: GMO-free
✅ Kosher & Halal: Religious certifications
✅ USDA Organic: USA approval
✅ Vegan: 100% vegetable

6. Controlled Origin

• Cultivation: Central India (Madhya Pradesh, Rajasthan) - ideal climate for maximum withanolides
• Traceability: Every batch traceable from field to final product
• Pesticide/heavy metal testing: Complies with EU/USA standards

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Ashwagandha KSM-66: 10 Scientifically Proven Benefits

1. Reduction of Stress and Anxiety 😌

Mechanism: Ashwagandha modulates HPA axis (hypothalamic-pituitary-adrenal), reducing cortisol secretion (stress hormone)

Evidence:

• Study Chandrasekhar et al. (2012): 600 mg KSM-66/day for 60 days → cortisol reduction -27.9%, perceived stress reduction -44% (PSS scale)
• Study Salve et al. (2019): 240-600 mg KSM-66/day for 60 days → reduction in anxiety -41% (HAM-A scale), improvement in quality of life +61%
• Meta-analysis 2020: 5 RCT studies show significant reduction in anxiety and stress with ashwagandha

Expected results:

• Feeling of calm and relaxation after 2-4 weeks
• Reduction of ruminative thoughts and anticipatory anxiety
• Improved management of stressful situations

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2. Improved Sleep Quality 😴

Mechanism: Ashwagandha increases GABA (inhibitory neurotransmitter), reduces nocturnal cortisol, promotes relaxation

Evidence:

• Study Deshpande et al. (2020): 600 mg KSM-66/day for 8 weeks → improvement in sleep quality +72% (PSQI scale), reduction in falling asleep latency, increase in deep sleep
• Study on insomnia: Reduction of nocturnal awakenings -42%, improvement in morning energy

Expected results:

• Faster falling asleep (10-15 min vs 30-45 min)
• Reduction of nocturnal awakenings
• Deeper, more restful sleep
• Waking up more rested

Optimal timing: Take 30-60 minutes before bedtime

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3. Increased Testosterone and Male Fertility 💪

Mechanism: Ashwagandha reduces testicular oxidative stress, improves LH (luteinizing hormone), reduces cortisol (testosterone antagonist)

Evidence:

• Study Wankhede et al. (2015): 300 mg KSM-66 2x/day for 8 weeks in trained men → increase in testosterone +17%, increase in muscle strength +15-17%, reduction in body fat -3.5%
• Study Ambiye et al. (2013): 675 mg/day for 90 days in infertile men → increase in testosterone +17%, increase in sperm count +167%, improvement in sperm motility +57%
• Study Ahmad et al. (2010): Improved sperm quality, reduction of seminal oxidative stress

Expected results (only in men with sub-optimal levels):

• Testosterone increase 10-20% in 8-12 weeks
• Improved libido and sexual function
• Increased energy and vitality
• Fertility support

⚠️ NOTE: Significant testosterone effect only in men with low/normal-low levels or under chronic stress. It is not a hormone booster in men with already optimal testosterone.

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4. Increased Muscle Strength and Athletic Performance 🏋️

Mechanism: Increased testosterone, reduced cortisol (catabolic hormone), improved recovery, supported protein synthesis

Evidence:

• Study Wankhede et al. (2015) (trained men):
  • Increase in lean mass +3.1 kg (vs. +1.4 kg placebo)
  • Increased bench strength +46 kg (vs +26 kg placebo)
  • Increased squat strength +14.5 kg (vs. +9.8 kg placebo)
  • Body fat reduction -3.5% (vs -1.5% placebo)
• Study Ziegenfuss et al. (2018): 600 mg KSM-66/day for 8 weeks → improvement in VO2max +13%, reduction in fatigue +12%

Expected results:

• Strength increase 10-20% in 8-12 weeks (with training)
• Improved muscle recovery
• Reduction of DOMS (post-workout soreness)
• Increased aerobic resistance 10-15%

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5. Cognitive and Memory Support 🧠

Mechanism: Neuroprotection (brain antioxidant), increased acetylcholine (memory neurotransmitter), reduced neuronal inflammation

Evidence:

• Study Choudhary et al. (2017): 600 mg KSM-66/day for 8 weeks → improvement in immediate memory +13%, delayed memory +22%, information processing speed +18%
• Study on adults with mild cognitive impairment: Improved attention, concentration, executive functions

Expected results:

• Improved memory (remembering names, information)
• Increased concentration and focus (2-4 weeks)
• Reduction of mental fog (brain fog)
• Improved multitasking

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6. Reduction of Body Weight and Fat (Stress-Related) 🍽️

Mechanism: Reduction of cortisol → reduction of emotional hunger, reduction of visceral fat accumulation, improvement of metabolism

Evidence:

• Study Choudhary et al. (2016): 600 mg KSM-66/day for 8 weeks in stressed subjects → body weight reduction -3%, BMI reduction -3.1%, emotional hunger reduction -22%
• Elevated cortisol promotes abdominal fat accumulation and carbohydrate/sugar hunger

Expected results (only in subjects with chronic stress):

• Reduction of nervous/emotional hunger
• Weight reduction 2-4 kg in 8-12 weeks (with low-calorie diet)
• Visceral fat reduction
• Improved appetite control

⚠️ NOTE: Ashwagandha is NOT a fat burner. Slimming effect is indirect (via reduction of cortisol/stress eating).

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7. Immune System Support 🛡️

Mechanism: Modulation of innate immunity (macrophages, NK cells), reduction of chronic inflammation, antioxidant

Evidence:

• Study Mikolai et al. (2009): Increased immunoglobulins (IgG, IgM), increased NK lymphocytes
• Immunomodulatory properties: Withanolides activate macrophages, reduce inflammatory cytokines (IL-6, TNF-α)

Expected results:

• Reduction in the frequency of respiratory infections
• Faster recovery from illnesses
• Reduction of chronic inflammation

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8. Thyroid Support (Subclinical Hypothyroidism) 🦋

Mechanism: Ashwagandha stimulates T4/T3 production, supports T4→T3 conversion, reduces thyroid oxidative stress

Evidence:

• Study Sharma et al. (2018): 600 mg KSM-66/day for 8 weeks in subclinical hypothyroidism → increased TSH normalization, increased T3/T4
• Greater effect in subclinical hypothyroidism (TSH 4.5-10 mIU/L)

Expected results (only in subclinical hypothyroidism):

• TSH normalization
• Increased energy and metabolism
• Reduction of hypothyroid symptoms (fatigue, coldness, weight)

⚠️ ATTENTION:

• Hyperthyroidism: CONTRAINDICATED (may worsen)
• Autoimmune thyroiditis: Consult endocrinologist
• Levothyroxine therapy: Possible interaction (monitor TSH)

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9. Reduction of Inflammation and Oxidative Stress 🔬

Mechanism: Witanolides are powerful antioxidants, reduce free radicals, inhibit NF-kB (inflammation factor)

Evidence:

• Reduction of inflammatory markers: CRP (C-reactive protein) -36%, IL-6 -15-25%
• Increased antioxidant enzymes: SOD (superoxide dismutase), catalase, glutathione peroxidase

Expected results:

• Reduction of systemic inflammation
• Cellular protection from aging
• Cardiovascular health support

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10. Menopause Support and Women's Health 👩

Mechanism: Reduction of cortisol, hormonal balance, reduction of hot flashes (GABA-like action)

Evidence:

• Study Deshpande et al. (2015): 600 mg KSM-66/day for 8 weeks → reduction in hot flashes -30%, improvement in sleep quality, reduction in menopausal anxiety
• Female libido support: Preliminary studies show improved sexual desire in women

Expected results:

• Reduction of hot flashes and night sweats
• Improved mood and peri-menopausal anxiety
• Sleep support
• Possible improvement in libido

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Dosage and Method of Use

Standard Dosage BPR Nutrition

• 1 tablet per day (500 mg KSM-66® extract = 25 mg withanolides)
• With plenty of water (200-300ml)
• With or without food (preferable with a light meal to reduce possible mild nausea)

Optimal Timing

1. EVENING (30-60 min before bedtime) ⭐⭐⭐⭐⭐

• Better for: Stress, anxiety, sleep, night recovery
• Why: GABA-like relaxing effect promotes deep sleep
• Dosage: 1 tablet (500 mg)

2. MORNING (with breakfast) ⭐⭐⭐⭐☆

• Better for: Sustained energy, daytime stress management, cognitive performance
• Why: Adaptogenic support to face the day
• Dosage: 1 tablet (500 mg)

3. SPLIT (morning + evening) ⭐⭐⭐⭐⭐

• Only for dosages >600 mg/day (studies use 600-1200 mg)
• Dosage: If you buy 2 packs, you can take 2 tablets/day (1000 mg) divided morning + evening
• Quando: Severe stress, athlete performance goals, testosterone

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Protocols for Specific Objective

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How Long to See Results?

• Stress/anxiety: 2-4 weeks (first sensations), 8 weeks (maximum effect)
• Sleep: 1-2 weeks (initial improvement), 4-8 weeks (optimal)
• Testosterone/strength: 4-8 weeks (blood changes), 8-12 weeks (maximum effects)
• Cognitive: 4-8 weeks
• Weight: 8-12 weeks (combined with diet)

⚠️ IMPORTANT: Ashwagandha is a long-term adaptogen, NOT an immediate-acting drug. Benefits accumulate gradually.

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Ashwagandha KSM-66: Who is it suitable for?

✅ People under chronic stress: Work, family, responsibility
✅ Those who suffer from mild-moderate anxiety: Generalized, social, anticipatory anxiety
✅ Insomnia and sleep disorders: Difficulty falling asleep, awakenings at night
✅ Athletes and bodybuilders: Strength, recovery, testosterone, endurance
✅ Men with low/normal-low testosterone: Natural support hormone levels
✅ Students and professionals: Memory, concentration, stress management
✅ Over 40: Cognitive support, energy, hormonal balance
✅ Women in menopause: Hot flashes, anxiety, sleep, hormonal balance
✅ Those looking for stress-related weight reduction: Emotional hunger, elevated cortisol
✅ Immune system support: Reduction of frequent infections
✅ Subclinical hypothyroidism: (Consult endocrinologist)

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Allergens and Warnings

Allergens

✅ Gluten free
✅ Lactose free
✅ Without soy
✅ 100% Vegan: Plant extract + plant excipients
⚠️ May contain traces: Eggs, soybeans, milk, fish (multi-product plant production)

General Warnings

• Food supplements they do not replace a varied and balanced diet and a healthy lifestyle
• Hold out of reach of children under 3 years
• Do not exceed 1 tablet per day (unless otherwise indicated by a professional)
• Not intended to diagnose, treat, cure, or prevent any disease
• Consult a doctor in case of:
  • Pregnancy or breastfeeding: Ashwagandha is CONTRAINDICATED (possible stimulation of uterine contractions, effects on fetus/newborn unknown)
  • Thyroid pathologies: Hyperthyroidism (CONTRAINDICATED), hypothyroidism (monitor TSH), autoimmune thyroiditis
  • Autoimmune diseases: Lupus, rheumatoid arthritis, multiple sclerosis (ashwagandha can stimulate immune system)
  • Diabetes: Ashwagandha can lower blood sugar (monitor, possible medication adjustment)
  • Hypertension/Hypotension: Ashwagandha can modulate pressure (monitor)
  • Gastrointestinal disorders: Ulcer, gastritis, GERD (ashwagandha may increase gastric acidity)
  • Scheduled surgical interventions: Discontinue 2 weeks before (possible effect on anesthesia/blood sugar)

⚠️ ABSOLUTE CONTRAINDICATIONS

• Pregnancy: Possible miscarriage (stimulation of contractions)
• Breastfeeding: Passage of active ingredients into milk (effects on newborns unknown)
• Hyperthyroidism: Ashwagandha stimulates thyroid (may worsen)
• Prostate cancer: Ashwagandha can increase testosterone (consult oncologist)

Pharmacological interactions

• Immunosuppressants (corticosteroids, cyclosporine): Ashwagandha may reduce effectiveness
• Thyroid hormones (levothyroxine): Possible potentiation of effect (monitor TSH)
• Sedatives/Benzodiazepines: Possible strengthening of the sedative effect (risk of excessive drowsiness)
• Antidiabetics (insulin, metformin): Possible hypoglycemia (monitor blood sugar)
• Antihypertensives: Possible effect enhancement (monitor pressure)

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Possible Side Effects (Rare)

Mild (5-10% users)

• Gastric disorders: Nausea, mild acidity (take with food)
• Diarrhoea: Rare, dose-dependent
• Daytime sleepiness: If taken in the morning in sensitive subjects (move to the evening)

Rare (<1%)

• Allergic reactions: Skin rash (discontinue use)
• Elevation of liver enzymes: Very rare (isolated cases in the literature with very high doses >1500 mg/day)

Overdose (>2000 mg/day)

• Vomiting, severe diarrhea, marked drowsiness
• Safe dosage: Up to 1200-1500 mg/day for 12 weeks (clinical studies)

⚠️ BPR Nutrition (500 mg/day) is WELL BELOW safety limits

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Quality and Certifications BPR Nutrition + KSM-66®

✅ KSM-66® Patent: Premium root extract with origin certification
✅ Titrated 5% Withanolides: Guaranteed standardization (25 mg per tablet)
✅ Over 22 Clinical Studies: KSM-66® is the most studied ashwagandha
✅ GMP (Good Manufacturing Practices): Pharmaceutical production
✅ ISO 9001: Quality management
✅ HACCP: Food safety
✅ Organic Certified: Raw material from organic farming
✅ Non-GMO Project: GMO-free
✅ Vegan Certified: 100% vegetable
✅ Kosher & Halal: Religious certifications
✅ Heavy metal and pesticide testing: Complies with EU standards
✅ Batch traceability: Each package traceable from field to product

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Ashwagandha KSM-66: FAQ (Frequently Asked Questions)

1. What is the difference between KSM-66® and generic ashwagandha?

KSM-66®:

• Extracted only from root (most powerful part)
• Standardized 5% withanolides (guaranteed)
• Over 22 clinical studies published
• Green Chemistry Process (water/ethanol only)
• Certifications: Organic, GMP, Non-GMO, Vegan
• Made in India (controlled origin)

Generic Ashwagandha:

• Root+leaf mix (variable withanolides 0.5-3%)
• No standardization guaranteed
• Few or no clinical studies
• Possible chemical solvents
• Variable or absent certifications

Verdict: KSM-66® costs 10-20% more, but guarantees efficacy, safety and purity scientifically proven.

2. Does Ashwagandha cause drowsiness during the day?

Rarely. Ashwagandha is a adaptogen, not a sedative. Effect is relaxation and calm, not drowsiness. If daytime drowsiness:

• Take in the evening instead of in the morning
• Check quality of sleep at night (ashwagandha improves sleep → more energy during the day)

3. Can I take ashwagandha with caffeine?

Yes, no problem. Ashwagandha + caffeine = useful synergy:

• Caffeine → energy and focus
• Ashwagandha → reduces caffeine jitter and anxiety, prolongs energy

4. How long does it take for ashwagandha to take effect?

• Acute effects (relaxation): 30-90 min post-dose (mild)
• Cumulative effects (stress, cortisol, sleep): 2-4 weeks
• Maximum effects (testosterone, strength, cognitive): 8-12 weeks

Ashwagandha is marathon, not sprint.

5. Should I do on/off cycles with ashwagandha?

Not mandatory, but recommended:

• Continuous use: 8-12 weeks
• Pause: 2-4 weeks
• Then start again

Why pause? Avoid tolerance (receptor downregulation), allow natural reset. Some users take continuously without problems.

6. Does Ashwagandha always lower testosterone or increase it?

INCREASES testosterone only in men with low/normal-low levels or under chronic stress. If testosterone is already optimal (>500-600 ng/dL), there is little or no effect. Ashwagandha is NOT a steroid, it works by reducing cortisol (testosterone antagonist).

7. Can I take ashwagandha if I have Hashimoto's thyroid?

Consult endocrinologist. Hashimoto's thyroiditis is autoimmune. Ashwagandha can:

• Pro: Reduce inflammation, support thyroid function
• Against: Stimulate the immune system (possible worsening of autoimmunity in some cases)

Evidence: Preliminary studies show benefit in hypothyroidism, but limited Hashimoto's data. Monitor TSH, anti-thyroid antibodies with an endocrinologist.

8. Is Ashwagandha bad for the liver?

Very rare. Isolated cases of elevated liver enzymes (AST/ALT) reported in the literature with very high doses (>1500 mg/day) or contaminated products. KSM-66® 500 mg/day BPR Nutrition is safe. If pre-existing liver disease, consult a hepatologist.

9. Can I give ashwagandha to children?

NO, under 18 years old. Pediatric studies are lacking. Ashwagandha can influence hormonal development (testosterone, thyroid). Only under pediatrician supervision for specific indications (severe anxiety, ADHD - off-label).

10. Does Ashwagandha help you lose weight?

Indirectly, YES (only in subjects with chronic stress and high cortisol):

• Reduces cortisol → reduces visceral fat accumulation
• Reduces emotional hunger/stress-eating
• Improve sleep → optimal metabolism

It is NOT a direct fat burner. You need a low-calorie diet + exercise. Ashwagandha facilitates adherence and reduces psychological obstacles.

11. Can I take ashwagandha if I take antidepressants (SSRIs)?

Consult psychiatrist. Ashwagandha has mild anxiolytic/antidepressant properties. Possible synergy with SSRIs, but also possible risk serotonin syndrome (rare). Monitor symptoms (agitation, confusion, tachycardia). Generally safe, but better to inform doctor.

12. How much does KSM-66® ashwagandha cost compared to generic?

Cost per dose:

• BPR Ashwagandha KSM-66® 500 mg: €0.43/dose (60 tablets at €25.90)
• Generic Ashwagandha 500 mg: €0.20-0.30/dose

BPR quantity discount: 3+ packs → €21.24 (-18%) = €0.35/dose

Verdict: KSM-66® costs +30-50%, but guarantees scientifically proven effectiveness, purity, safety. Worth every penny.

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Comparison: KSM-66® BPR vs Ashwagandha Generica vs Sensoril®

Verdict:

• KSM-66® → Best for athletic performance, testosterone, strength
• Sensoril® → Best for acute stress, immediate sleep (more withaferin = more sedative but potentially more toxic long term)
• Generic → Economical but unpredictable effectiveness

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Why Buy on Wellfitstore.com

✅ Original BPR Nutrition Products: 100% authentic KSM-66®, tamper-evident seal
✅ Fast Shipping: Delivery to Italy in 2-5 working days
✅ Secure Payments: SSL, PayPal, credit cards, bank transfer
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✅ Easy Return: 30 days money back guarantee
✅ Loyalty Program: Accumulate points on every purchase
✅ Verified Reviews: Over 4.6/5 stars for Ashwagandha KSM-66®
✅ Quantity discount: 3+ packs -18% (€21.24 instead of €25.90)
✅ Transparency: Complete product sheets, visible certifications
✅ Privacy Guaranteed: Data protected according to GDPR

🛒 Order now at www.wellfitstore.com
📧 Do you have questions? Write to info@wellfitstore.com

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Storage and Duration

• Temperature: Store at 15-25°C, in a cool, dry place
• Avoid: Heat, direct light, humidity
• After opening: Close the jar tightly, consume within 24 months
• Shelf life: 36 months from production (check expiry date on the packaging)

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Conclusion: Ashwagandha KSM-66 - The Adaptogen of the 21st Century

Ashwagandha KSM-66 it's not just a supplement, it's 3000 years of Ayurvedic wisdom validated by modern science. With beyond 22 clinical studies published, KSM-66® is the most studied, safe and effective ashwagandha extract in the world.

BPR Nutrition Ashwagandha 60 tablets offers you 500 mg of KSM-66® per dose (25 mg titrated withanolides), the same formula used in studies that demonstrated:

• ✅ Stress/cortisol reduction -27.9%
• ✅ Testosterone increase +17%
• ✅ Increased muscle strength +15-17%
• ✅ Sleep quality improvement +72%
• ✅ Memory improvement +22%

Not all ashwagandhas are the same. Choose KSM-66®, choose certified quality, choose scientifically proven results. 🌿💪😌

🛒 Buy Ashwagandha KSM-66® on Wellfitstore.com
📧 Support: info@wellfitstore.com
🌐 www.wellfitstore.com

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Scientific References:

• Chandrasekhar K, et al. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012
• Wankhede S, et al. Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. J Int Soc Sports Nutr. 2015
• Hi J, et al. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults. Cureus. 2019
• Deshpande A, et al. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha extract on sleep quality in healthy adults. Sleep Med. 2020
• Choudhary D, et al. Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract. J Evid Based Complementary Altern Med. 2017