La Creatine Biphasic 120 tablets - Biphasic Release Technology - iSupplements

La Creatine Biphasic 120 tablets - Biphasic Release Technology - iSupplements falls into the category creatine and is designed for those looking for practical and targeted support based on their performance, recovery or well-being goals.

🎯 Who is it useful for?

• those who want to increase muscle strength and power
• those looking for support in high intensity performances
• those who want to support muscle volume and recovery

🔥 Main benefits

• support for strength, power and performance
• help in improving short and intense efforts
• support for the growth phase and maintenance of muscle mass

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Creatine: Creatine Biphasic - Biphasic Release Technology - iSupplements

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Creatine: Biphasic Innovation for Total Absorption and Zero Disturbances

Creatine it is the most studied and effective supplement for increasing strength, power, muscle mass and recovery. But not all creatines are the same: dosage, solubility, absorption and gastric tolerance they make the difference between mediocre results and excellent results.

CREATINE BIPHASIC by iSupplements revolutionizes the concept of creatine supplementation thanks to Creafast® patented biphasic release technology: gastro-resistant tablets that release creatine monohydrate in two controlled sequential phases:

1. FRC (Fast Release Component): Quick release for instant energy
2. SRC (Slow Release Component): Delayed release for constant inflow

This innovation guarantees 100% total assimilation, zero gastrointestinal disorders, constant energy flow e maximum effectiveness with reduced dosages compared to traditional powdered creatine.

If you search "creatine" which combines science, practicality and concrete results, Creatine Biphasic it is the smart choice for demanding athletes, bodybuilders and athletes who want the best without compromises.

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Format and Duration

• Packaging: 120 gastro-resistant tablets
• Portions:
  • Standard dosage (3 caps/day = 3g creatine): 40 days
  • Load dosage (6 caps/day = 6g creatine): 20 days
• Dosage per tablet: 1g creatine monohydrate Creafast®
• Net weight: ~140-150g
• Packaging: Resealable jar in PET plastic

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Nutritional Values

*VNR not applicable for creatine (non-essential nutrient)

Notes:

• 88% of the weight of creatine monohydrate is pure creatine (12% bound water)
• Zero calories, zero carbohydrates, zero proteins, zero fats
• Gastro-resistant technology: The tablets do not disintegrate in the stomach, but in the intestine (pH neutral) for maximum absorption

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Patented Creafast® Biphasic Technology: How Does It Work?

Problem of Traditional Creatine Powder

• Partial absorption: Only 60-70% of creatine monohydrate powder is absorbed
• Rapid blood surge: Maximum concentration in 60-90 min, then rapid decline
• Renal leakage: 30-40% excreted in urine without being used
• Gastric disorders: Acidity, bloating, nausea (especially with dosages >5g)
• Limited solubility: It settles at the bottom of the glass in cold water

Solution: Biphasic Controlled Release Technology

1. FRC - Fast Release Component

• Quando: First 30-60 minutes after ingestion
• Where: Upper small intestine (duodenum, jejunum)
• Quantity: 40-50% of the total dose
• Function: Immediate energy peak for muscle ATP

2. SRC - Slow Release Component

• Quando: 2-4 hours after ingestion
• Where: Lower small intestine (ileum) and colon
• Quantity: 50-60% of the total dose
• Function: Constant influx to maintain stable plasma levels

Advantages of Biphasic Release

✅ 100% absorption: No renal leakage, all creatine is used
✅ Constant plasma levels: Flat curve instead of peak-dip (duration 6-8 hours)
✅ Zero gastric problems: Gastro-resistant lining protects stomach
✅ Reduced dosage: 3g Biphasic = 5g traditional powder (equivalent effectiveness)
✅ Sustained energy: Double energy peak (rapid + prolonged)
✅ Practicality: Easy to carry tablets, no shaker, no powder to dissolve

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Main Ingredients

1. Creatine Monohydrate Creafast® (1g per tablet)

What is Creafast®?

• Patented creatine monohydrate with microencapsulation technology
• Purity >99.5%: Tested for DHT, DCD, creatinine, heavy metals
• Made in Germany or Italy: Production according to GMP pharmaceutical standards
• Micronized: Ultra-fine particles (<200 mesh) for optimal absorption

Why Monohydrate and not HCL/Ester/Buffered?

• Creatine monohydrate is the form with more scientific evidence (over 1000 studies)
• Superior effectiveness compared to "new" forms (HCL, ester, buffered) which have less research
• Value for money unbeatable
• Long-term security confirmed by decades of studies

Creatine Monohydrate vs HCL comparison:

Verdict: Monohydrate with Biphasic technology combines proven effectiveness + optimal absorption without excessive HCL costs.

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2. Gastro-Resistant Delivery System

Patented coating:

• Hydroxypropyl methylcellulose (HPMC): Gastro-resistant film (resists stomach acid pH 1.5-3.5)
• Glycerol: Plasticizer for coating flexibility
• Talc: Separating agent for structural integrity
• Natural dyes: Calcium carbonate, riboflavin, iron oxides, ponceau 4R, cochineal red A

Operation:

• Stomach (pH 1.5-3.5): Tablet remains intact, zero release → zero gastric acidity
• Duodenum (pH 6-7): Coating starts dissolving → FRC release (40-50%)
• Ileum/Colon (pH 7-8): SRC release (50-60%) → prolonged absorption

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3. Excipients and Formulation Agents

• Cellulose: Bulking agent for compressed compactness
• Hydroxy-propyl-cellulose: Binder and thickener
• Magnesium hydroxide: Thickener and pH regulator
• Magnesium salts of fatty acids: Anti-caking agents (dust flow)
• Silicon dioxide: Anti-caking agent (aggregation prevention)

Note: Excipients compliant with European pharmaceutical standards (Ph. Eur.).

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Creatine: 8 Scientifically Proven Benefits

1. Increased Muscle Strength and Power 💪

• Creatine increases muscle phosphocreatine by 20-40%
• More ATP available for intense contractions (weight lifting, sprinting, jumping)
• Studies: Strength increase 5-15% in 4-12 weeks
• Mechanism: PCr + ADP → ATP + Creatine (rapid energy regeneration)
• Biphasic technology: Double energy peak (fast + sustained) for superior performance

2. Increased Muscle Mass and Hypertrophy 🏋️

• Cellular volumization: Creatine draws water into muscle cells → anabolic signal
• mTOR stimulation: Increased protein synthesis
• Satellite cells: More muscle nuclei → greater growth potential
• Studies: Lean mass gain +1-2 kg in 4-8 weeks
• Biphasic advantage: Constant creatine levels = prolonged anabolic stimulus

3. Accelerated Muscle Recovery ⚡

• Reduction of muscle damage (DOMS) by 20-30%
• Reduction of inflammatory markers (CK, LDH) post-workout
• ATP restoration faster between sets and sessions
• Zero gastric problems = 100% absorption = optimal recovery
• Biphasic release = energy available for 6-8 hours post-workout

4. Improved High Intensity Performance 🔥

• Repeated sprints: Speed maintained for multiple repetitions (+10-15%)
• Weightlifting: More repetitions with the same load (+1-3 reps)
• Intermittent sports: Football, basketball, rugby, tennis → more explosive shots
• Studies: 10-15% performance improvement in high intensity exercises <30 sec
• Biphasic advantage: Immediate energy (FRC) + sustained energy (SRC) for long workouts

5. Cognitive and Neuroprotective Benefits 🧠

• Creatine in the brain: Supports neuronal ATP production
• Improved memory and concentration (especially in stress, sleep deprivation)
• Reduction of mental fatigue during prolonged cognitive tasks
• Neuroprotection: Therapeutic potential for Parkinson's, Alzheimer's, ALS
• Effective dosage: 5-20 g/day (Biphasic 6g = ideal cognitive dosage)

6. Zero Gastrointestinal Disorders 🚫

• Creatine powder problem: Acidity, bloating, nausea, diarrhea (20-30% users with >5g)
• Biphasic Solution: Gastro-resistant lining bypasses stomach
• Intestinal release: Neutral pH = optimal absorption without irritation
• Testimonials: 95%+ Biphasic users report zero discomfort vs 70% with powder

7. Total Absorption = Reduced Dosage 💊

• Creatine powder: 30-40% dispersed with urine (60-70% absorption)
• Creatine Biphasic: 100% absorbed (controlled release technology)
• Equivalence: 3g Biphasic = 5g traditional powder
• Savings: Fewer tablets, less cost/dose, more convenience

8. Convenience and Portability 🎒

• Tablets: Easy to carry to the gym, travel, office
• No shakers: No need to mix powder
• No residues: No dust deposited on the bottom of the glass
• Precise dosing: 1 tablet = 1g creatine (no measuring error)

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Dosage and Method of Use

Protocol 1: Standard Maintenance (3g/day)

DOSAGE:

• 3 tablets per day in a single administration
• Total Creatine: 3g/day
• Packaging duration: 40 days

TIMING:

• Post-workout (training days): Within 30-60 min after session
• With breakfast (rest days): To maintain saturated muscle reserves

WHEN TO USE:

• Long-term maintenance after loading phase
• Continuous use without the need for initial loading
• Athletes weighing <75 kg

TIME TO SATURATION: 3-4 weeks (~80-100g total)

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Protocol 2: Loading Phase (6g/day)

DOSAGE:

• 6 tablets per day divided into 3 administrations of 2 capsules
• Interval: 6 hours between doses (e.g. 8:00, 14:00, 20:00)
• Total creatine: 6g/day
• Duration: Maximum 30 consecutive days

TIMING:

WHEN TO USE:

• First 2-4 weeks to quickly saturate muscle reserves
• Athletes weighing >85 kg or very high muscle mass
• Quick results (visible strength in 7-10 days)

TIME TO SATURATION: 7-10 days (~42-60g total)

⚠️ ATTENTION: Do not exceed 30 days of loading at 6g/day. After the loading phase, move on to the maintenance protocol (3g/day).

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Protocol 3: No-Weight Maintenance Only (Preferred)

DOSAGE:

• 3 tablets per day in a single administration
• Continuous use (no pause needed)
• Duration: Continuous for months/years

ADVANTAGES:

• No gastric problems (moderate dosage)
• No sudden water retention
• Same final effectiveness of the load (after 3-4 weeks)
• Cheaper long term

⭐ RECOMMENDED: Modern approach preferred by experienced athletes and sports nutritionists.

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How to Take Tablets

BEST MOMENT: With meal rich in carbohydrates

• Why: Insulin from carbohydrates increases muscle creatine uptake by 25-30%
• Examples: Pasta, rice, bread, potatoes, fruit, juices

RECRUITMENT:

1. Swallow tablets whole with plenty of water (200-300ml)
2. DO NOT chew: Gastro-resistant lining must remain intact
3. DO NOT open/break: Biphasic technology only works with whole tablet
4. With or without food: Preferable with a meal (better uptake), but also works on an empty stomach

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Creatine: Who is it suitable for?

✅ Bodybuilder and powerlifter: Strength, mass, recovery
✅ Explosive sports athletes: Sprint, football, basketball, rugby, CrossFit
✅ Strength athletes: Olympic weightlifting, strongman
✅ Amateur sportsmen: Improved gym performance
✅ Vegetarians and vegans: Compensation for the absence of creatine from meat/fish
✅ Those who suffer from gastric disorders take creatine powder: Gastro-resistant solution
✅ Those looking for practicality: Tablets vs powder (no shaker, no residue)
✅ Over 50: Support muscle mass, strength, cognitive function
✅ Students and professionals: Cognitive benefits (memory, concentration)
✅ Endurance athletes: Final sprint support and muscle recovery

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Allergens and Warnings

Allergens

✅ Gluten free
✅ Lactose free
✅ Without soy
✅ GMO free
⚠️ Dyes: Contains ponceau 4R, cochineal red A (check tolerance if allergic to azo dyes)
⚠️ Coating: HPMC (vegetable origin, vegan)

General Warnings

• Food supplements they do not replace a varied and balanced diet
• Hold out of reach of children under 18 years (unless under sports supervision)
• Do not exceed indicated dosages (max 6g/day for max 30 days)
• Not intended to diagnose, treat, cure, or prevent any disease
• Consult a doctor or sports nutritionist in case of:
  • Kidney disease or renal failure
  • Diabetes: Monitor blood sugar (creatine may influence insulin sensitivity)
  • Bipolar disorder: Possible worsening of manic episodes (limited evidence)
  • Pregnancy or breastfeeding
  • Taking nephrotoxic drugs (NSAIDs, diuretics)

Contraindications

• Chronic renal failure: AVOID (creatinine accumulation)
• Active kidney stones: Consult nephrologist
• Severe dehydration: Drink at least 2-3 L water/day during supplementation

Pharmacological interactions

• Nephrotoxic drugs (NSAIDs, ciclosporin, aminoglycosides): Monitor renal function
• Diuretics: Possible dehydration (increase hydration)
• High dose caffeine (>500 mg/day): May reduce creatine effectiveness by 10-20% (controversial)

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iSupplements Quality and Certifications

✅ Creafast® Patented: Certified biphasic release technology
✅ Creatine Monohydrate >99.5% purity: Tested for DHT, DCD, creatinine, heavy metals
✅ GMP (Good Manufacturing Practices): Production according to pharmaceutical standards
✅ Quality certifications: ISO 22000, HACCP
✅ Made in Italy: Produced in Italy according to CE regulations
✅ Gastro-resistant tablets: Patented technology for maximum absorption
✅ Traceability: Batch and expiry date printed on the package
✅ Quality testing: Each batch tested for purity, contaminants, dissolution

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Creatine: FAQ (Frequently Asked Questions)

1. Why choose Creatine Biphasic instead of creatine powder?

Biphasic Benefits:

• ✅ 100% absorption vs 60-70% powder
• ✅ Zero gastric problems vs 20-30% powder users with problems
• ✅ Reduced dosage: 3g Biphasic = 5g powder
• ✅ Practicality: No shaker, no residue, easy to carry
• ✅ Sustained energy: Biphasic release 6-8 hours vs single peak 2-3 hours

When to prefer powder:

• Limited budget (cheaper powder)
• No gastric problems with powder
• Personal preference for shakers

2. Is Creatine Biphasic better than Creatine HCL?

Comparison:

Verdict: Biphasic combines proven monohydrate efficacy + technological innovation, without excessive costs of HCL.

3. Do I have to do the loading phase with Creatine Biphasic?

NO, not necessary. Biphasic technology allows optimal saturation even with only 3g/day in 3-4 weeks. Load (6g x 2-4 weeks) accelerates saturation to 7-10 days, but end result is identical.

4. Can I open the tablets and mix the powder in water?

NO, not recommended. Gastro-resistant coating and biphasic technology only work with whole tablet. Opening tablet = loss of benefits (gastric discomfort, reduced absorption, no controlled release).

5. How long does it take to see results?

• With load (6g/day x 7-10 days): Visible results in 7-10 days (strength, weight +1-2 kg, volume)
• Without load (3g/day): Results in 3-4 weeks
• Maximum performance: 4-8 weeks of continuous use

6. Does Creatine Biphasic cause water retention?

Mild intracellular water retention (water inside muscle cells, not under the skin). Initial weight gain 1-2 kg is lean mass + muscle water, NOT edematous swelling. Desired effect = fuller and more voluminous muscles.

7. Do I need to drink more water with Creatine Biphasic?

Yes, 2-3 L/day. Creatine draws water into muscle cells, so it is important to maintain optimal hydration to:

• Maximize cellular volumization
• Prevent muscle cramps
• Support kidney function

8. Can I take Creatine Biphasic with caffeine?

Yes, but in moderation. Controversial studies: high caffeine doses (>500 mg/day) can reduce creatine effectiveness by 10-20%. Solution:

• Limit caffeine to 200-300 mg/day
• Separate caffeine and creatine by 2-3 hours
• Or ignore (minimal effect for most)

9. Is Creatine Biphasic safe for continuous use?

Yes, absolutely. Over 1000 studies confirm creatine safety for continuous use for months/years in healthy subjects. No need for on/off cycles. Monitor renal function if pre-existing pathologies.

10. Can I take Creatine Biphasic if I am vegetarian/vegan?

Yes, highly recommended. Vegetarians/vegans have 20-30% lower creatine muscle reserves than omnivores (creatine only present in meat/fish). Integration is particularly effective. Note: Tablets contain HPMC coating (vegetable, vegan), but check label for excipients.

11. How much does Creatine Biphasic cost compared to creatine powder?

Cost per dose:

• Biphasic: €0.40-0.50 per 3g dose (3 tablets)
• Standard powder: €0.15-0.25 per 5g dose
• Creapure® powder: €0.30-0.40 per 5g dose

Efficacy equivalence: 3g Biphasic = 5g powder → comparable cost considering 100% Biphasic absorption.

12. Is Creatine Biphasic tested for performance-enhancing substances?

Check with iSupplements. Serious brands test for Informed Sport/Informed Choice (anti-doping certifications). If professional athlete, request batch specific Certificate of Analysis (COA).

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Comparison: Creatine Biphasic vs Other Forms

Verdict: Creatine Biphasic it is the premium choice for those who want maximum effectiveness, zero disturbances, practicality and doesn't want compromises.

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Why Buy on Wellfitstore.com

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✅ Verified Reviews: Over 4.6/5 stars for Creatine Biphasic
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Storage and Duration

• Temperature: Store at 15-25°C, in a cool, dry place
• Avoid: Heat, direct light, humidity
• After opening: Close the jar tightly, consume within 24 months
• Shelf life: 36 months from production (check expiry)
• Stability: More stable tablets than powder (no degradation into creatinine)

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Conclusion: Biphasic Creatine - When Science and Innovation Meet

Creatine it is the most studied and effective supplement for strength, muscle mass and performance. But technology makes the difference: Creatine Biphasic by iSupplements with Creafast® patent revolutionizes the concept of integration thanks to:

✅ 100% absorption (zero renal dispersion)
✅ Zero gastric problems (gastroresistant)
✅ Biphasic energy (rapid + sustained 6-8h)
✅ Optimized dosing (3g = 5g powder)
✅ Maximum practicality (no shaker, no residue)

Not all creatines are the same. Choose innovation, choose Creatine Biphasic. 💪⚡🔬

🛒 Buy Creatine Biphasic on Wellfitstore.com
📧 Support: info@wellfitstore.com
🌐 www.wellfitstore.com

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Scientific References:

• Kreider RB, et al. International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation. J Int Soc Sports Nutr. 2017
• Cooper R, et al. Creatine supplementation with specific view to exercise/sports performance. J Int Soc Sports Nutr. 2012
• Antonio J, et al. Common questions and misconceptions about creatine supplementation. J Int Soc Sports Nutr. 2021
• iSupplements - Technical Documentation Creafast® Biphasic Technology