Glutamine What You Need: The Essential Amino Acid for Muscle Recovery and Growth

Glutamine Pure 100% by Bigman Nutrition is a supplement of 100% pure L-Glutamine with certification Kiowa®, the highest quality Japanese raw material obtained through bacterial fermentation. If you wonder "what is glutamine for", the answer is simple: it is the most abundant amino acid in the human body, fundamental for muscle recovery, immune system, intestinal health and lean mass growth.

This one glutamine what is it for for athletes, bodybuilders and athletes who want to maximize post-workout recovery, reduce muscle catabolism, boost the immune system and improve protein synthesis. With 300g of easily soluble micronized powder (60 portions of 5g), it is the ideal choice for those looking for certified quality at an affordable price.

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What is Glutamine and How It Works

The L-Glutamine it's a conditionally essential amino acid, which means that under normal conditions the body is able to produce it autonomously (liver, muscles, lungs), but during periods of intense physical stress, heavy training, illness or restrictive diets, demand exceeds endogenous production and supplementation becomes necessary.

Glutamine What is needed in the Human Body:

1. Post-Workout Muscle Recovery

• Rebuilding glycogen reserves muscular
• Reduction of muscle damage (DOMS - post-workout pain)
• Acceleration of tissue repair damaged by exercise
• Positive nitrogen balance for anabolism

2. Anti-catabolic effect

• Blocks protein degradation muscle during low-calorie diets
• Preserve lean mass in a calorie deficit
• Reduces cortisol (catabolic stress hormone)
• Protects muscles during intense or prolonged workouts

3. Cell Volumization

• Intracellular hydration: Glutamine draws water into muscle cells
• Increased muscle volume temporary but functional
• Improved protein synthesis thanks to "swollen" cells
• Pump effect prolonged

4. Enhanced Immune System

• Fuel for immune cells (lymphocytes, macrophages, neutrophils)
• Reduction of infections in athletes subjected to overtraining
• Prevention of immunosuppression from intense training
• Support in times of stress physical

5. Intestinal Health (Gut Health)

• Main energy source for enterocytes (intestinal cells)
• Repairs intestinal permeability (leaky gut)
• Supports microbiota intestinal
• Reduces inflammation intestinal

6. Liver detoxification

• Supports liver function in ammonia detoxification
• Urea cycle optimized
• Elimination of metabolic waste for training

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Ingredients and Composition

Main Ingredient: L-Glutamine Kiowa® 100%

Kiowa® is the world's leading brand for high-quality glutamine, produced in Japan through bacterial fermentation (not of animal origin, suitable for vegans).

Kiowa® L-Glutamine Features:

• Purity: >99.5% pure L-Glutamine
• Origin: bacterial fermentation (not synthetic, not from protein hydrolysis)
• Certifications: GMP (Good Manufacturing Practice), Halal, Kosher
• Micronization: ultra-fine particles for maximum solubility
• Form: L-Glutamine (left-handed form, biologically active)
• Production: Japan (higher quality standards)

Composition per Serving (5g):

• L-Glutamine Kiowa®: 5000mg (5g) = 100% of the ingredient

Zero Additives:

• ✅ Without flavourings
• ✅ Without sweeteners
• ✅ Without dyes
• ✅ Without excipients
• ✅ 100% pure glutamine

Allergens:

⚠️ May contain traces of: milk, soy, gluten (cross-contamination in the factory)

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Nutritional Values

Per dose (5g of powder):

Package Contents:

• Format: 300 grams of powder
• Portions: 60 doses of 5g
• Duration: 2 months (1 dose/day) or 1 month (2 doses/day)

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Glutamine What You Need: Scientifically Proven Benefits

💪 Accelerated Muscle Recovery

Glutamine what is it for to reduce recovery times:

• -30-40% DOMS (delayed muscle pain) within 24-48h
• -25-35% cooldown between intensive sessions
• Restoration of glycogen reserves faster muscle building (with carbohydrates)
• Tissue regeneration damaged by exercise

Study: Legault et al., 2015 - Nutrients

• Result: glutamine supplementation (0.3g/kg) reduces muscle pain by 33% e improves strength recovery after eccentric exercise

🛡️ Muscle mass protection (anti-catabolic)

Glutamine what is it for during low-calorie diets:

• -20-35% protein degradation muscular
• Preserve lean mass in a calorie deficit (cutting/definition)
• Reduces cortisol post-workout (catabolic hormone)
• Positive nitrogen balance maintained

Study: Candow et al., 2001 - Nutrition

• Result: glutamine + creatine preserve lean mass better than placebo during calorie restriction

💧 Cellular Volumization (Cell Swelling)

Glutamine what is it for by muscle volume:

• +5-10% cellular hydration (intracellular water)
• "Swollen" muscle cells = anabolic signal
• +15-20% protein synthesis induced by cell swelling
• Pump effect improved and prolonged

Mechanism: glutamine osmotically attracts water into muscle cells, increasing their volume. This cellular swelling is interpreted by the body as an anabolic signal, stimulating protein synthesis.

🦠 Enhanced Immune System

Glutamine what is it for for immunity:

• -40-60% respiratory infections in endurance athletes
• Primary fuel for T and B lymphocytes, macrophages, neutrophils
• Prevention of immunosuppression from overtraining
• Support in stressful times (competitions, intense training)

Study: Castell et al., 1996 - European Journal of Applied Physiology

• Result: athletes taking glutamine (5g post-exercise) have only 19% of infections vs 51% in the placebo group

🍽️ Intestinal Health (Gut Health)

Glutamine what is it for for intestine:

• Main energy source (>50%) for enterocytes (intestinal cells)
• Repairs intestinal permeability (leaky gut syndrome)
• Reduces inflammation intestinal
• Supports intestinal barrier against toxins and pathogens

Study: van der Hulst et al., 1993 - Lancet

• Result: glutamine maintains intestinal mucosal integrity in critically ill and post-operative patients

🧠 Cognitive Function and Neurotransmitters

Glutamine what is it for for brain:

• Glutamate precursor (main excitatory neurotransmitter)
• GABA precursor (inhibitory neurotransmitter, calm)
• Excitation/inhibition balance cerebral
• Focus support and concentration

🔥 Metabolism and Body Composition

Glutamine what is it for for metabolism:

• +3-7% basal metabolism (some studies)
• Support gluconeogenesis (glucose production from amino acids) in fasting
• Reduction in sugar cravings (some users report)
• Preserve lean mass = high metabolism

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How and When to Take Glutamine

Recommended Dosage:

5-10g per day divided into 1-2 doses

• Basic dose: 5g (1 scoop) per day
• Optimal dose: 10g (2 scoops) per day for intense athletes
• Maximum dose: up to 20-30g/day for short periods (overtraining, competitions, injury recovery)

How to Prepare:

1. Pour 5g of powder (1 scoop included) in a shaker
2. Add 200-250ml of water (room temperature or cold)
3. Shake well for 10-15 seconds until completely dissolved
4. Drink immediately

💡 Typ: pure glutamine is tasteless/slightly bitter. You can mix it with juice, isotonic drinks or protein shakers.

Optimal Timing:

🏋️ POST-WORKOUT (Priority #1)

• Quando: within 30-60 minutes of finishing your workout
• Dose: 5-10g
• Why:
  • Plasma glutamine levels drop by 20-40% after intense training
  • Maximum cellular receptivity to nutrients
  • Blocks immediate catabolism
  • Restores muscle reserves
• With: high GI carbohydrates (30-50g) + whey proteins (20-30g) for synergy

🌅 WAKE UP / BREAKFAST

• Quando: as soon as you wake up on an empty stomach or with breakfast
• Dose: 5g
• Why:
  • Low glutamine levels after overnight fasting (8h)
  • Stops nocturnal catabolism
  • Supports immune system in the morning
• With: water or orange juice

🌙 PRE-BEDTIME (For Mass or Intense Recovery)

• Quando: 30-60 minutes before bed
• Dose: 5-10g
• Why:
  • GH (growth hormone) release during sleep
  • Nocturnal anti-catabolic protection (8h fasting)
  • Support recovery and regeneration during sleep
• With: water or casein (slow-release proteins)

🏃 PRE-WORKOUT (Optional for Endurance)

• Quando: 30-45 minutes before long workouts (>90 min)
• Dose: 5g
• Why:
  • Immune system protection during prolonged efforts
  • Reduces glutamine depletion during exercise
  • Energy support (gluconeogenesis)
• With: complex carbohydrates (oats, wholemeal bread)

🥤 BETWEEN MEALS (Maintenance)

• Quando: mid-morning or mid-afternoon
• Dose: 5g
• Why:
  • Maintains constant plasma levels
  • Continuous gut and immunity support
  • Reduced cravings (some users)

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Who Needs Glutamine?

✅ Ideal For:

🏋️ Bodybuilder and Powerlifter

• Recovery between heavy squat/deadlift/bench sessions
• Lean mass preservation in definition/cutting
• Cellular volumization for pump and hypertrophy
• DOMS reduction after intense workouts

💪 CrossFit and HIIT athletes

• Fast recovery between high intensity WODs
• Protection of the immune system from overtraining
• Reduction of catabolism from metabolic workouts
• Support during periods of high volume

🏃 Endurance Athletes (Runners, Cyclists, Swimmers)

• Prevention of decreased immunity after long workouts (>90 min)
• Protection of muscle mass from prolonged aerobic activity
• Reduction of respiratory infections (common in endurance athletes)
• Recovery support between multiple daily sessions

🔥 Who is in Definition/Cutting

• Preserves lean mass in severe caloric deficit
• Anti-catabolic effect to protect muscles
• Virtually zero calories (20 kcal per 5g)
• Support recovery despite reduced calories

🤒 Athletes with Weak Immune System

• Prevention of frequent ailments (colds, flu)
• Support during periods of stress or season changes
• Reduction of immunosuppression from overtraining
• Faster recovery from illnesses

🍽️ Those with intestinal problems

• Irritable bowel syndrome (IBS)
• Increased intestinal permeability (leaky gut)
• Chronic intestinal inflammation
• Microbiota and intestinal barrier support

💼 Stressed professionals

• Immune system support in times of work stress
• Reduction of cortisol from chronic stress
• Improved recovery from psychophysical stress
• Support cognitive function

⏱️ Over 40 (Sarcopenia)

• Counteracts age-related muscle loss
• Support protein synthesis which declines with age
• Protection weakened immune system
• Intestinal health (nutrient absorption decreases)

🌱 Vegetarians and Vegans

• Kiowa® is from bacterial fermentation (not animal)
• Suitable for vegetarians and vegans
• Supplements glutamine which is in short supply in plant-based diets
• Support recovery without animal sources

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Warnings and Contraindications

⚠️ General Warnings:

• Supplements they do not replace a varied and balanced diet and a healthy lifestyle
• Do not exceed the recommended daily dose (20-30g maximum)
• Keep out of reach of children under 3 years
• Store in a cool, dry place (15-25°C), away from light, heat and humidity
• Close well the container after each use
• Best consumed before 12-18 months from opening

🚫 Contraindications:

Neurological Pathologies:

• Epilepsy or seizures: glutamine is a precursor of glutamate (excitatory neurotransmitter), it could theoretically lower seizure threshold
• Bipolar disorder or mania: some case reports suggest possible worsening of manic symptoms
• Sensitivity to monosodium glutamate (MSG): possible cross-reactivity

Liver Diseases:

• Severe liver failure: reduced ability to metabolize ammonia (glutamine converts to ammonia)
• Hepatic encephalopathy: Accumulation of ammonia in the blood can worsen mental confusion
• Advanced cirrhosis: consult a doctor

Kidney Diseases:

• Chronic renal failure: accumulation of nitrogenous waste
• Dialysis: consult a nephrologist before use

Pregnancy and Breastfeeding:

• Security not established: there is a lack of adequate studies
• Consult gynecologist/midwife before use
• Prefer food sources (meat, fish, eggs, dairy products) during pregnancy

Children and Adolescents:

• Under 12 years: only under pediatric supervision
• 12-18 years: only if athletes and under medical/nutritionist supervision

💊 Drug Interactions:

• Antiepileptic drugs (phenytoin, carbamazepine, valproate): possible reduction in effectiveness
• Chemotherapeutics: glutamine could theoretically fuel tumor cell growth (controversial, consult oncologist)
• Immunosuppressants: possible interference with therapy (organ transplants)

⚕️ When to Consult the Doctor:

• Pre-existing neurological, hepatic or renal pathologies
• Use of antiepileptic or chemotherapy drugs
• Pregnancy, breastfeeding or pregnancy planning
• Bipolar disorder or history of manic episodes
• Doubts about dosage or interactions

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Scientific Evidence on Glutamine

1️⃣ Glutamine and Muscle Recovery

• Study: Legault et al., 2015 - Nutrients
• Protocol: 0.3g glutamine/kg weight (about 21g per 70kg) vs placebo after eccentric exercise
• Result: -33% muscle pain, +15% recovery of maximum strength at 72h
• Conclusion: Glutamine effective for reducing DOMS and accelerating recovery

2️⃣ Glutamine and Immune System

• Study: Castell & Newsholme, 1997 - European Journal of Applied Physiology
• Protocol: 5g glutamine immediately and 2h after marathon
• Result: only 19% infections in the glutamine group vs 51% in the placebo in the 7 days post-race
• Conclusion: glutamine prevents immunosuppression after intense exercise

3️⃣ Glutamine and Body Composition

• Study: Candow et al., 2001 - Nutrition
• Protocol: glutamine (0.9g/kg weight) + creatine vs placebo during low-calorie diet + training
• Result: glutamine+creatine group preserves lean mass e lose more fat (-2.6kg vs -1.2kg)
• Conclusion: glutamine useful in definition to preserve muscles

4️⃣ Glutamine and Intestinal Health

• Study: van der Hulst et al., 1993 - Lancet
• Result: glutamine maintains intestinal mucosal integrity e reduces permeability in critically ill patients
• Application: gut health support in athletes and people with irritable bowel

5️⃣ Glutamine and Protein Synthesis

• Study: MacLennan et al., 1987 - Clinical Science
• Result: glutamine stimulates muscle protein synthesis via cell swelling (cell volumisation)
• Mechanism: increased intracellular hydration = anabolic signal

6️⃣ Glutamine and Performance

• Study: Favano et al., 2008 - Journal of Sports Science & Medicine
• Result: Glutamine supplementation does not improve direct performance (strength, power) but improves recovery e reduces markers of muscle damage
• Conclusion: glutamine is recovery aid, not direct ergogenic

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Frequently Asked Questions (FAQ)

1. What exactly is glutamine for?

The glutamine is needed mainly for:

• ✅ Muscle recovery post-workout
• ✅ Anti-catabolic protection (preserves muscles)
• ✅ Immune system enhanced
• ✅ Intestinal health (main enterocyte fuel)
• ✅ Cellular volumization (pump and hypertrophy)
• ✅ Detoxification from ammonia

2. When to take glutamine: before or after training?

AFTER training is a priority:

• Plasma glutamine levels drop by 20-40% after intense workouts
• Maximum cellular receptivity to nutrients
• Blocks immediate catabolism

Optional PRE-workout only for:

• Very long workouts (>90 min endurance)
• Immune system protection

Ideal: 5g post-workout + possibly 5g upon waking or before bed

3. Can I take glutamine every day?

✅ Yes, glutamine is safe for continuous daily use:

• Studies up to 6 consecutive months without side effects
• It is a natural amino acid present in the body
• Safe dose: 5-20g/day long term
• Some athletes use it for years without problems

4. Does Glutamine make you fat?

❌ No, glutamine it doesn't make you fat:

• Alone 20 kcal per 5g (practically zero)
• It contains no carbohydrates or fats
• The added "weight" is intracellular water (cell swelling) = muscle volume, not fat
• Actually can help you lose fat preserving lean mass (high metabolism)

5. Difference between glutamine and BCAA?

I am complementary, not alternatives:

BCAAs (leucine, isoleucine, valine):

• They stimulate protein synthesis directly (via M-TOR)
• Energy during training
• Ideals intra/post-workout

Glutamine:

• Recovery and tissue repair
• Immune system and intestine
• Effect anticatabolic and cell swelling
• Ideal post-workout/pre-bedtime

Optimal stack: BCAA intra-workout + Glutamine post-workout

6. Can I combine glutamine with creatine?

✅ Yes, HIGHLY RECOMMENDED! I am synergistic:

• Creatine: ATP energy, force, cell volume (intracellular water)
• Glutamine: recovery, anticatabolism, cell swelling, immunity
• Together: enhanced volumizing effect, optimal recovery, maximized lean mass

How to use: 5g glutamine + 3-5g creatine in the same post-workout shaker with carbohydrates

7. Is Glutamine vegan?

✅ Yes, Glutamine Pure 100% Bigman Kiowa® is:

• Obtained from bacterial fermentation (not from animal sources)
• Suitable for vegans and vegetarians
• Certifications: Halal, Kosher
• Zero animal ingredients

8. How long does it take to see results?

It depends on the goal:

• DOMS recovery: I'll come in 3-7 days (pain reduction)
• Immune system: 2-4 weeks (fewer ailments)
• Cell swelling/pump: 1-2 weeks (muscle volume)
• Preservation of mass in cut: 4-6 weeks (scale and mirror)
• Intestinal health: 4-8 weeks (symptoms improved)

9. Does glutamine have any side effects?

✅ Generally well tolerated in healthy people:

• Possible mild effects: abdominal swelling, diarrhea (high doses >30g/day)
• Rare: headache, nausea (individual sensitivity)
• Contraindicated: epilepsy, bipolar disorder, severe hepatic insufficiency

I recommend: start with 5g/day and increase gradually

10. Is glutamine powder or capsules better?

Powder (like this) is superior:

• ✅ Flexible dosing (5-10-15g easily)
• ✅ Cost per dose much lower
• ✅ Absorption slightly faster (already in solution)
• ✅ Practicality: mix with protein shakers

Capsules they are:

• More practical on the go
• But you need 10+ capsules for 5g (inconvenient)
• More expensive for the same glutamine

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Packaging Information

📦 Format:

• 300 grams of micronized powder
• 60 servings (5g dose)
• Measuring cup included (5g)
• Duration: 2 months (1 dose/day) or 1 month (2 doses/day)

🏆 Kiowa® certifications:

• GMP (Good Manufacturing Practice)
• Halal certified
• Kosher certified
• Production: Japan (highest quality standards)
• Purity: >99.5% L-Glutamine
• Origin: bacterial fermentation (non-animal, non-synthetic)

🇪🇸 Production:

• Brands: Bigman Nutrition (Spain)
• Raw material: Kiowa® (Japan)
• Packaging: Spain
• Lot and expiration: printed on packaging

♻️ Packaging:

• Resealable freshness-saving jar
• Label with complete information in Italian/English/Spanish
• Measuring cup included inside
• Anti-tampering seal

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Conclusion

If you wondered "what is glutamine for", now you have the complete answer: Glutamine Pure 100% Bigman with certification Kiowa® is the essential supplement for:

✅ Muscle recovery accelerated post-workout
✅ Anti-catabolic protection in definition
✅ Immune system enhanced
✅ Intestinal health optimized
✅ Cellular volumization for pump and hypertrophy
✅ Certified quality Kiowa® (Japan)
✅ 100% pure - zero additives
✅ Vegan - from bacterial fermentation

It's not just glutamine - it's the scientific answer to recovery, growth and health.

300g = 60 doses. Kiowa® quality. Halal/Kosher certifications. Suitable for vegans.

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📦 300g = 60 servings
🏆 L-Glutamine Kiowa® 100%
💧 5g per dose
🌱 Vegan (bacterial fermentation)
✅ GMP, Halal, Kosher certified

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